iexplore.exe generated errors

[playmecat]

Everytime download from rapidshare or megaupload on mozilla I get "iexplore.exe has generated errors" and then closes the download. IE gets this message when IE starts up. I do not use IE anymore, but how do I get rid of this on mozilla? Any thoughts greatly appreciated. Very frustrated

[Spider]

Hi playmecat welcome to CyberTechHelp.

You most likely have multiple spyware infections.
Is that computer still able to use a browser? In my signature (below) is ewido SPYWARE SCAN. Scan everything.